I have an international group of postdocs and PhD students who focus on molecular transport processes in polarized cells, including brain endothelial cells. I am also a passionate microscopist and have helped establish imaging networks such as Danish BioImaging and Bridging Nordic Bioimaging
Life expectancy is increasing worldwide, which means that more individuals will develop neurodegenerative diseases such as Alzheimer's and Parkinson's. Treating these and other brain diseases is complicated because the brain is protected by a so-called blood-brain barrier, which is very selective in what it allows to pass through. Thus, it is difficult for medicine to reach its target in the brain.
We work with various blood-brain barrier models in our laboratory, where we investigate the possibility of using different receptors to transport drugs across the blood-brain barrier. In our work, we use advanced microscopy to understand the molecular mechanisms.
I am part of the team that teaches medical students in their 3rd semester of biochemistry. With my background in chemistry, I have co-authored a book on Medical Chemistry with colleagues, which is used in the subject of cell biology for first-semester medical students.
In addition to my position as a professor of neuroscience, I am the director of the faculty's imaging core facility and deputy institute leader at the Institute of Biomedicine.