Development of vectors for delivery of RNA- and protein-based therapeutics - including microRNA and CRISPR/Cas9 - to cells or tissue including the eye.
We focus on AAV- and LV-based vectors for treatment of retinal diseases, including age-related macular degeneration. We explore Dicer-independent RNAi systems to silence and express of multiple genes simultaneously in our combinatorial gene therapy.
Teaching in Genetics and Personalized Medicine.
Supervision of postdocs, PhD students, master's and undergraduate students.
Development of viral vectors for treatment of retinal diseases, including age-related macular degeneration and diabetic retinopathy.
Reviewer for scientific journals, including Nature and Molecular Therapy
