Institut for Biologi

Aarhus Universitets segl

Biofilm group

The group

Group photo

My research combines microbiology and nanotechnology in pursuit of understanding how biofilms establish, and how they can be controlled.

  • Investigation of fundamental mechanisms in bacterial adhesion and biofilm formation, particularly the role of extracellular DNA.
  • Development of new approaches to  control biofilms and treat biofilm infections through targeted drug delivery, novel antibiotics and nanobiotics, and non-biocidal biofilm control with e.g. enzymes or salinity oscillation.

2025 highligts

Ajunwa, O. M., Minero, G. A. S., Jensen, S. D. & Meyer, R. L. (2025). Hemin-binding DNA structures on the surface of bacteria promote extracellular electron transfer. Nucleic Acids Research, 53(15), Article gkaf790. https://doi.org/10.1093/nar/gkaf790

Dybtved, M. S., Petersen, M. E., Firdausy, A. F., Johansen, M. I., Faddy, E., Gadeberg, C., Østergaard, L., Jørgensen, N. P., Glud, L. N., Søgaard, A. B., Meyer, R. L. & Zelikin, A. N. (2025). Broad-Spectrum Antimicrobial Treatment Targeted Through Drug Conjugation to Vancomycin. Advanced Healthcare Materials, Article e03932. Advance online publication. https://doi.org/10.1002/adhm.202503932

Evans, D. C. S., Kristensen, M. F., Minero, G. A. S., Palmén, L. G., Knap, I., Tiwari, M. K., Schlafer, S. & Meyer, R. L. (2025). Dental biofilms contain DNase I-resistant Z-DNA and G-quadruplexes but alternative DNase overcomes this resistance. npj Biofilms and Microbiomes, 11(1), Article 80. https://doi.org/10.1038/s41522-025-00694-x

Petersen, M. E., Khamas, A. B., Østergaard, L. J., Jørgensen, N. P. & Meyer, R. L. (2025). Combination therapy delays antimicrobial resistance after adaptive laboratory evolution of Staphylococcus aureus. Antimicrobial Agents and Chemotherapy, 69(4), Article e01483-24. https://doi.org/10.1128/aac.01483-24

Del Rey, Y. C., Rikvold, P. D., Lund, M. B., Raittio, E. J., Schramm, A., Meyer, R. L. & Schlafer, S. (2025). Arginine modulates the pH, microbial composition, and matrix architecture of biofilms from caries-active patients. International Journal of Oral Science, 17(1), Article 70. https://doi.org/10.1038/s41368-025-00404-5

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Recent publications

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Gutierrez, O., Mohanakrishnan, J., Sharma, K. R., Meyer, R. L., Keller, J. & Juan, Z. (2008). Evaluation of oxygen injection as a means of controlling sulfide production in a sewer system. Water Research, 42(17), 4549-4561.
Arpanaei, A., Pillai, S., Meyer, R. L., Besenbacher, F., Bernbom, N., Jensen, R. L., Gram, L., Enghild, J. J., Petersen, S. V. & Kingshott, P. (2008). Fish Protein Adsorption to Different Surfaces and Anti-cell Adhesive Properties of Adsorbed Layers.. Afhandling præsenteret på How to Look at Protein Adsorption - A Practical Approach, Copenhagen University, Copenhagen, Danmark.
Nielsen, J. L., Meyer, R. L., Xia, Y., Kong, Y. & Nielsen, P. H. (2008). Identification and characterization of the fermenting microbial community in enhanced biological phosphorus removal plants. Afhandling præsenteret på International symposium for microbial ecology (ISME), Cairns, Australia, August 2008, Cairns, Australien.
Meyer, R. L., Iversen, A., Pillai, S., Bischoff, C. & Besenbacher, F. (2008). Nanofunctionalised sol-gel surface coatings for biofilm prevention. Afhandling præsenteret på Nanotech Northern Europe, Copenhagen, Danmark.
Meyer, R. L., Allen, D. E. & Smith, S. (2008). Nitrification and denitrification as sources of sediment nitrous oxide production: A microsensor study. Marine Chemistry, 110(1-2), 68.
Mohanakrishnan, J., Gutierrez, O., Meyer, R. L. & Yuan, Z. (2008). Nitrite effectively inhibits sulfide and methane production in a laboratory scale sewer reactor. Water Research, 42(14), 3961-3971.
Pillai, S., Arpanaei, A., Meyer, R. L., Besenbacher, F. & Kingshott, P. (2008). Preventing fibrinogen and HSA adsorption by coating surfaces with aqueous extracts of fish proteins.. Afhandling præsenteret på 8th World Biomaterials Congress, Amsterdam, Holland.

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Revideret 09.07.2026
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Anne Kirstine Mehlsen