Cellular responses to temperature are the foundation of thermal acclimation and adaptation, which allows animals to thrive in very different thermal environments. We study how temperature acclimation and adaptation affects the 1) activity and regulation of proteins and 2) composition of membrane lipids to understand how these macromolecular modifications affect rates of active and passive transport over membranes. The goal of this research is to understand 3) how temperature affects organisms’ to maintain physiological homeostasis in the intracellular and extracellular compartments and 4) how cellular responses are linked to organismal capacity at high and low temperature.
